Ancillary · AlphaStack™ Compound Database

Anastrozole

Also known as: Arimidex · Adex · Anastro
WADA BannedAncillary

A non-steroidal third-generation aromatase inhibitor. Prescribed for hormone receptor-positive breast cancer in postmenopausal women. Used alongside aromatizing androgens to manage estrogen levels.

Side Effects & Risks

Performance Use

Anastrozole is not a performance compound in itself. Its function in performance settings is entirely supportive: managing the estrogen elevation that aromatizing androgens produce. Testosterone and other aromatizing compounds convert to estradiol via the aromatase enzyme, and at performance doses this conversion can produce gynecomastia, water ret...

Stacking & Combinations

Anastrozole is added to stacks that include aromatizing compounds, primarily testosterone and Boldenone. It is not combined with non-aromatizing compounds like Trenbolone, Masteron, or Stanozolol because those compounds do not require aromatase inhibition. When Masteron is included in a stack, some athletes reduce or eliminate Anastrozole because M...

Real-World Risk

The most common and practically significant risk of Anastrozole is overuse. Estrogen is not purely a problem to be eliminated. It plays essential roles in joint health, cardiovascular protection, mood regulation, libido, and bone density. Crashing estrogen with excessive Anastrozole use produces a c...

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