Hormone · AlphaStack™ Compound Database

IGF-1 LR3

Also known as: Long R3 IGF-1 · Insulin-like Growth Factor 1 · IGF-1
WADA BannedHormone

Side Effects & Risks

Performance Use

IGF-1 LR3 is used in advanced performance protocols specifically for the muscle hyperplasia effect — the potential to increase the actual number of muscle cells rather than just their size. This is theoretically a permanent change that persists after the compound clears. It is used post-workout for local injections into trained muscle or systemical...

Stacking & Combinations

IGF-1 LR3 appears in the most advanced protocols alongside HGH and insulin. The three compounds work through related but distinct pathways — HGH stimulates IGF-1 production and metabolic changes, exogenous IGF-1 LR3 provides direct receptor activation at the muscle level, and insulin manages glucose and amplifies nutrient partitioning. This combina...

Real-World Risk

The proliferative mechanism that makes IGF-1 LR3 interesting for muscle development is not tissue-specific. IGF-1 receptor activation promotes cell growth in all tissues including existing tumors or pre-cancerous cells. The chronic elevation of a potent growth factor in a system that may contain und...

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